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1

Advances in menaquinone biosynthesis: sublocalisation and allosteric regulation

Johnston, Jodie M, Bulloch, Esther MM

Journal:

Current Opinion in Structural Biology

Year:

2020

File:

PDF, 2.84 MB

2020

2

Detection of Covalent Intermediates Formed in the Reaction of 4-Amino-4-deoxychorismate Synthase

Esther M. M. Bulloch, Chris Abell

Journal:

Year:

2005

Language:

english

File:

PDF, 69 KB

english, 2005

3

Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI)

Alexandra Manos-Turvey, Esther M. M. Bulloch, Peter J. Rutledge, Edward N. Baker, J. Shaun Lott, Richard J. Payne

Journal:

Year:

2010

Language:

english

File:

PDF, 497 KB

english, 2010

4

Cover Picture: Inhibition Studies of Mycobacterium tuberculosis Salicylate Synthase (MbtI) (ChemMedChem 7/2010)

Alexandra Manos-Turvey, Esther M. M. Bulloch, Peter J. Rutledge, Edward N. Baker, J. Shaun Lott, Richard J. Payne

Journal:

Year:

2010

Language:

english

File:

PDF, 930 KB

english, 2010

5

Unambiguous determination of isobaric histone modifications by reversed-phase retention time and high-mass accuracy

Lanhao Yang, Shengjiang Tu, Chen Ren, Esther M.M. Bulloch, Chung-Lin Liao, Ming-Daw Tsai, Michael A. Freitas

Journal:

Analytical Biochemistry

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

6

Inhibition of chorismate-utilising enzymes by 2-amino-4-carboxypyridine and 4-carboxypyridone and 5-carboxypyridone analogues

Payne, Richard J., Bulloch, Esther M. M., Kerbarh, Olivier, Abell, Chris

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

7

Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site

Manos-Turvey, Alexandra, Cergol, Katie M., Salam, Noeris K., Bulloch, Esther M. M., Chi, Gamma, Pang, Angel, Britton, Warwick J., West, Nicholas P., Baker, Edward N., Lott, J. Shaun, Payne, Richard J.

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

8

Synthesis and evaluation of 2,5-dihydrochorismate analogues as inhibitors of the chorismate-utilising enzymes

Payne, Richard J., Bulloch, Esther M. M., Toscano, Miguel M., Jones, Michelle A., Kerbarh, Olivier, Abell, Chris

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

9

Design and synthesis of aromatic inhibitors of anthranilate synthase

Payne, Richard J., Bulloch, Esther M. M., Abell, Andrew D., Abell, Chris

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 216 KB

english, 2005

10

Design and synthesis of aromatic inhibitors of anthranilate synthase

Payne, Richard J., Toscano, Miguel D., Bulloch, Esther M. M., Abell, Andrew D., Abell, Chris

Journal:

Organic & Biomolecular Chemistry

Year:

2005

Language:

english

File:

PDF, 359 KB

english, 2005

11

Protein domain definition should allow for conditional disorder

Yegambaram, Kavestri, Bulloch, Esther M.M., Kingston, Richard L.

Journal:

Protein Science

Year:

2013

Language:

english

File:

PDF, 14.92 MB

english, 2013

12

Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

Evans, Genevieve L., Gamage, Swarna A., Bulloch, Esther M. M., Baker, Edward N., Denny, William A., Lott, J. Shaun

Journal:

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

13

Substrate Deactivation of Phenylalanine-Sensitive 3-Deoxy- d - arabino -heptulosonate 7-Phosphate Synthase by Erythrose 4-Phosphate †

Parker, Emily J., Bulloch, Esther M. M., Jameson, Geoffrey B., Abell, Chris

Journal:

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

14

Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis

Chi, Gamma, Manos-Turvey, Alexandra, O’Connor, Patrick D., Johnston, Jodie M., Evans, Genevieve L., Baker, Edward N., Payne, Richard J., Lott, J. Shaun, Bulloch, Esther M. M.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.19 MB

english, 2012

15

Transient Dimerization of Human MxA Promotes GTP Hydrolysis, Resulting in a Mechanical Power Stroke

Rennie, Martin L., McKelvie, Siri A., Bulloch, Esther M.M., Kingston, Richard L.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.24 MB

english, 2014

16

Identifying protein domains by global analysis of soluble fragment data

Bulloch, Esther M.M., Kingston, Richard L.

Journal:

Analytical Biochemistry

Year:

2014

Language:

english

File:

PDF, 1.53 MB

english, 2014

17

Hydrolysis of the 5‘- p -Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III †

Hamdan, Samir, Bulloch, Esther M., Thompson, Phillip R., Beck, Jennifer L., Yang, Ji Yeon, Crowther, Jeffrey A., Lilley, Penelope E., Carr, Paul D., Ollis, David L., Brown, Susan E., Dixon, Nicholas E

Journal:

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

18

Identification of 4-Amino-4-deoxychorismate Synthase as the Molecular Target for the Antimicrobial Action of (6 S )-6-Fluoroshikimate

Bulloch, Esther M. M., Jones, Michelle A., Parker, Emily J., Osborne, Andrew P., Stephens, Elaine, Davies, Gareth M., Coggins, John R., Abell, Chris

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 60 KB

english, 2004

19

Removal of the C-Terminal Regulatory Domain of α-Isopropylmalate Synthase Disrupts Functional Substrate Binding

Huisman, Frances H. A., Koon, Nayden, Bulloch, Esther M. M., Baker, Heather M., Baker, Edward N., Squire, Christopher J., Parker, Emily J.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.70 MB

english, 2012

20

The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition

Castell, Alina, Short, Francesca L., Evans, Genevieve L., Cookson, Tammie V. M., Bulloch, Esther M. M., Joseph, Dmitri D. A., Lee, Clare E., Parker, Emily J., Baker, Edward N., Lott, J. Shaun

Journal:

Year:

2013

Language:

english

File:

PDF, 4.45 MB

english, 2013

21

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

Cookson, Tammie, Castell, Alina, Bulloch, Esther, Evans, Genevieve, Short, Francesca, Baker, Edward, Lott, J, Parker, Emily

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 2.31 MB

english, 2014

22

Adverse Consequences of Glucocorticoid Medication: Psychological, Cognitive, and Behavioral Effects

Judd, Lewis L., Schettler, Pamela J., Brown, E. Sherwood, Wolkowitz, Owen M., Sternberg, Esther M., Bender, Bruce G., Bulloch, Karen, Cidlowski, John A., Ronald de Kloet, E., Fardet, Laurence, Joëls,

Journal:

American Journal of Psychiatry

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

23

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis , reveals an unusual acyl-binding pocket

Chai, Ai-Fen, Bulloch, Esther M. M., Evans, Genevieve L., Lott, J. Shaun, Baker, Edward N., Johnston, Jodie M.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2015

Language:

english

File:

PDF, 2.29 MB

english, 2015

24

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

Chai, Ai-Fen, Johnston, Jodie M., Bunker, Richard D., Bulloch, Esther M. M., Evans, Genevieve L., Lott, J. Shaun, Baker, Edward N.

Journal:

Acta Crystallographica Section F Structural Biology and Crystallization Communications

Year:

2013

Language:

english

File:

PDF, 299 KB

english, 2013

25

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

Evans, Genevieve L., Gamage, Swarna A., Bulloch, Esther M. M., Baker, Edward N., Denny, William A., Lott, J. Shaun

Journal:

Year:

2015

Language:

english

File:

PDF, 267 KB

english, 2015

26

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

Jirgis, Ehab N.M., Bashiri, Ghader, Bulloch, Esther M.M., Johnston, Jodie M., Baker, Edward N.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.53 MB

english, 2016

27

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

Bashiri, Ghader, Nigon, Laura V., Jirgis, Ehab N. M., Ho, Ngoc Anh Thu, Stanborough, Tamsyn, Dawes, Stephanie S, Baker, Edward N., Bulloch, Esther M. M., Johnston, Jodie M.

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 3.80 MB

2020